Basic Information
| LncRNA/CircRNA Name | circNRIP1 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | renal cell carcinoma |
| ICD-0-3 | C64.9 |
| Methods | qPCR, CCK-8 and western blot |
| Sample | renal cell carcinoma?tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | We found that circNRIP1 was overexpressed in tumor tissue but miR-505 was overproduced. Silencing circZNF292 induced inhibition of cell viability, colony formation, and migration, as well as the activity of AMPK and PI3K/AKT/mTOR cascades but enhancement of apoptosis. |
| Pubmed ID | 31692056 |
| Year | 2019 |
| Title | The Circular RNA-NRIP1 Plays Oncogenic Roles by Targeting microRNA-505 in the Renal Carcinoma Cell Lines |
External Links
| Links for circNRIP1 | GenBank HGNC NONCODE |
| Links for renal cell carcinoma | OMIM COSMIC |