Basic Information
| LncRNA/CircRNA Name | circEZH2 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioma |
| ICD-0-3 | NA |
| Methods | qPCR, CCK-8, colony formation, flow cytometry, and transwell experiments |
| Sample | glioma tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | We identified that circ-EZH2 was overexpressed in glioma tissues and cell lines. Further studies revealed that ectopic expression of circ-EZH2 significantly promoted cell growth, migration and invasion but inhibited cell apoptosis. |
| Pubmed ID | 31669648 |
| Year | 2019 |
| Title | Circ-EZH2 Knockdown Reverses DDAH1 and CBX3-mediated Cell Growth and Invasion in Glioma Through miR-1265 Sponge Activity |
External Links
| Links for circEZH2 | GenBank HGNC NONCODE |
| Links for glioma | OMIM COSMIC |