Basic Information
| LncRNA/CircRNA Name | circ_0074026 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioma |
| ICD-0-3 | NA |
| Methods | qPCR, CCK-8 and cell invasion assays |
| Sample | glioma tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | The levels of circ_0074026 were both apparently increased in GM samples and cells. The elevated expression of circ_0074026 was linked to patients' tumor size, WHO grade, disease-free survival, and overall survival. The depletion of circ_0074026 can block cell growth, migration, invasion, and impel cell apoptosis in the LN229 cell line. |
| Pubmed ID | 31643077 |
| Year | 2019 |
| Title | Circular RNA circ_0074026 Indicates Unfavorable Prognosis for Patients With Glioma and Facilitates Oncogenesis of Tumor Cells by Targeting miR-1304 to Modulate ERBB4 Expression |
External Links
| Links for circ_0074026 | GenBank HGNC NONCODE |
| Links for glioma | OMIM COSMIC |