Basic Information
| LncRNA/CircRNA Name | circPVT1 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | esophageal cancer |
| ICD-0-3 | C15 |
| Methods | qPCR and western blot |
| Sample | esophageal cancer tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | we demonstrated a significant up-regulation of circPVT1 levels in EC tissues and cancer cell lines. These results suggested a potential role for circPVT1 in cell proliferation. In addition, overexpressing circPVT1 in TE-10 cell promoted invasive ability of cancer cell. |
| Pubmed ID | 31636510 |
| Year | 2019 |
| Title | Potential Role of circPVT1 as a Proliferative Factor and Treatment Target in Esophageal Carcinoma |
External Links
| Links for circPVT1 | GenBank HGNC NONCODE |
| Links for esophageal cancer | OMIM COSMIC |