Basic Information
| LncRNA/CircRNA Name | circTSPAN4 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung adenocarcinoma |
| ICD-0-3 | C34 |
| Methods | qPCR, luciferase reporter and RNA pull-down assays |
| Sample | lung adenocarcinoma tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | Circ-TSPAN4 was significantly upregulated in LUAD tissues and cell lines. The increased circ-TSPAN4 was linked to advanced tumor-node-metastasis stage, lymph node and distant metastasis, and poor outcome. |
| Pubmed ID | 31573758 |
| Year | 2019 |
| Title | Circular RNA circ-TSPAN4 Promotes Lung Adenocarcinoma Metastasis by Upregulating ZEB1 via Sponging miR-665 |
External Links
| Links for circTSPAN4 | GenBank HGNC NONCODE |
| Links for lung adenocarcinoma | OMIM COSMIC |