Basic Information
LncRNA/CircRNA Name | circTSPAN4 |
Synonyms | |
Region | |
Ensemble | |
Refseq |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | lung adenocarcinoma |
ICD-0-3 | C34 |
Methods | qPCR, luciferase reporter and RNA pull-down assays |
Sample | lung adenocarcinoma tissues and cell lines |
Expression Pattern | up-regulated |
Function Description | Circ-TSPAN4 was significantly upregulated in LUAD tissues and cell lines. The increased circ-TSPAN4 was linked to advanced tumor-node-metastasis stage, lymph node and distant metastasis, and poor outcome. |
Pubmed ID | 31573758 |
Year | 2019 |
Title | Circular RNA circ-TSPAN4 Promotes Lung Adenocarcinoma Metastasis by Upregulating ZEB1 via Sponging miR-665 |
External Links
Links for circTSPAN4 | GenBank HGNC NONCODE |
Links for lung adenocarcinoma | OMIM COSMIC |