Basic Information
| LncRNA/CircRNA Name | circPIP5K1A |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colon cancer |
| ICD-0-3 | C18 |
| Methods | qPCR |
| Sample | colon cancer tissue, cell lines and serum |
| Expression Pattern | up-regulated |
| Function Description | CircPIP5K1A was significantly upregulated in colon cancer tissue relative to their adjacent normal tissues. Knockdown of circPIP5K1A in colon cancer cells impaired cell viability and suppressed cell invasion and migration, while enforced expression of circPIP5K1A exhibited the opposite effects on cell migration. |
| Pubmed ID | 31558874 |
| Year | 2019 |
| Title | Circular RNA PIP5K1A Promotes Colon Cancer Development Through Inhibiting miR-1273a |
External Links
| Links for circPIP5K1A | GenBank HGNC NONCODE |
| Links for colon cancer | OMIM COSMIC |