Basic Information
| LncRNA/CircRNA Name | circ_0005576 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | cervical cancer |
| ICD-0-3 | C53 |
| Methods | qPCR |
| Sample | cervical cancer tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | irc_0005576 was significantly overexpressed in both CC tissues and cell lines. Furthermore, upregulated circ_0005576 was positively associated with advanced FIGO stage, lymph node metastasis, but was negatively related with overall survival of CC patients. Additionally, circ_0005576 knockdown induced a suppressed cell growth, colony formation and metastasis of HeLa and SiHa cells. |
| Pubmed ID | 31545253 |
| Year | 2019 |
| Title | Upregulated circ_0005576 Facilitates Cervical Cancer Progression via the miR-153/KIF20A Axis |
External Links
| Links for circ_0005576 | GenBank HGNC NONCODE |
| Links for cervical cancer | OMIM COSMIC |