Basic Information
| LncRNA/CircRNA Name | circLDLRAD3 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | pancreatic cancer |
| ICD-0-3 | C25 |
| Methods | qPCR, wound healing assay and transwell invasion assay |
| Sample | pancreatic cancer tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | Increased expression of circ-LDLRAD3 was indicative of a poor prognosis in patients with pancreatic cancer. Knockdown of circ-LDLRAD3 repressed the growth of pancreatic cancer in vitro and in vivo. |
| Pubmed ID | 31521692 |
| Year | 2019 |
| Title | Downregulation of Circular RNA circ-LDLRAD3 Suppresses Pancreatic Cancer Progression Through miR-137-3p/PTN Axis |
External Links
| Links for circLDLRAD3 | GenBank HGNC NONCODE |
| Links for pancreatic cancer | OMIM COSMIC |