Basic Information
| LncRNA/CircRNA Name | circPTN |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioma |
| ICD-0-3 | NA |
| Methods | qPCR, Dual luciferase reporter system, biotin label RNA pull-down and FISH |
| Sample | glioma tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | We demonstrated circPTN was significantly higher expression in glioma tissues and glioma cell lines, compared with NBT and HEB (human astrocyte). In gain- and loss-of-function experiments, circPTN significantly promoted glioma growth in vitro and in vivo. |
| Pubmed ID | 31511040 |
| Year | 2019 |
| Title | circPTN Sponges miR-145-5p/miR-330-5p to Promote Proliferation and Stemness in Glioma |
External Links
| Links for circPTN | GenBank HGNC NONCODE |
| Links for glioma | OMIM COSMIC |