Basic Information
| LncRNA/CircRNA Name | circ_100876 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR, CCK-8, transwell and clone formation assays |
| Sample | breast cancer tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | circRNA_100876 level in BC tissues was conspicuously higher than that in the adjacent tissues, and the patients with distant metastasis had higher expression than those without. Moreover, patients with a high expression of circRNA_100876 had a relatively lower overall survival rate. Compared with the NC group, the cell proliferation and invasion ability of circRNA_100876 knockdown group was conspicuously decreased. |
| Pubmed ID | 31486496 |
| Year | 2019 |
| Title | CircRNA_100876 Promote Proliferation and Metastasis of Breast Cancer Cells Through Adsorbing microRNA-361-3p in a Sponge Form |
External Links
| Links for circ_100876 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |