Basic Information
| LncRNA/CircRNA Name | circ_0072309 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | renal cancer |
| ICD-0-3 | C64.9 |
| Methods | qPCR, western blot |
| Sample | renal cancer tissues and cell lines |
| Expression Pattern | down-regulated |
| Function Description | The hsa-circ-0072309 was poorly expressed in tumor tissue. Abundant hsa-circ-0072309 induced the inhibitions of cell proliferation, migration and invasion, as well as the PI3K/AKT and the mTOR cascades but enhancement of apoptosis. |
| Pubmed ID | 31456425 |
| Year | 2019 |
| Title | The Circular RNA hsa-circ-0072309 Plays Anti-Tumour Roles by Sponging miR-100 Through the Deactivation of PI3K/AKT and mTOR Pathways in the Renal Carcinoma Cell Lines |
External Links
| Links for circ_0072309 | GenBank HGNC NONCODE |
| Links for renal cancer | OMIM COSMIC |