Basic Information
| LncRNA/CircRNA Name | circNHSL1 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, Luciferase reporter, RNA immunoprecipitation (RIP) and rescued assays |
| Sample | gastric cancer tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | We found that the level of circNHSL1 was significantly up-regulated in gastric cancer, and positively correlated with clinicopathological features and poor prognosis of patients with gastric cancer. Functionally, circNHSL1 promoted cell mobility and invasion, as well as in vivo tumorgenesis and metastasis. |
| Pubmed ID | 31438963 |
| Year | 2019 |
| Title | Circular RNA circNHSL1 Promotes Gastric Cancer Progression Through the miR-1306-3p/SIX1/vimentin Axis |
External Links
| Links for circNHSL1 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |