Basic Information
LncRNA/CircRNA Name | circ_101882 |
Synonyms | |
Region | |
Ensemble | |
Refseq |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | apoptosis | Drug | ||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | gastric cancer |
ICD-0-3 | C16 |
Methods | qPCR, MTT assay, cell migration, and invasion assay, colony formation assay, and flow cytometric assay |
Sample | gastric cancer tissues and cell lines |
Expression Pattern | up-regulated |
Function Description | Hsa_circ_101882 expression levels were significantly increased in GC tissue and GC cell lines. Functionally, low expression of hsa_circ_101882 revealed anti-tumor effects via inhibiting cell growth, migration, and invasion and promoting cell apoptosis. Mechanically, the dysregulated expression of hsa_circ_101882 affects EMT signaling pathway |
Pubmed ID | 31420917 |
Year | 2019 |
Title | Hsa_circ_101882 Promotes Migration and Invasion of Gastric Cancer Cells by Regulating EMT |
External Links
Links for circ_101882 | GenBank HGNC NONCODE |
Links for gastric cancer | OMIM COSMIC |