Basic Information
| LncRNA/CircRNA Name | circITGA7 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR, western blot, CCK8, colony formation |
| Sample | colorectal cancer tissues |
| Expression Pattern | down-regulated |
| Function Description | CircRNA sequencing analysis suggested that compared to that in adjacent normal control tissue, the expression of circ-ITGA7, a novel circRNA, is decreased significantly in CRC. Gain-of-function studies further demonstrated that circ-ITGA7 suppressed proliferation of CRC cells. |
| Pubmed ID | 31372051 |
| Year | 2019 |
| Title | Circ-ITGA7 Sponges miR-3187-3p to Upregulate ASXL1, Suppressing Colorectal Cancer Proliferation |
External Links
| Links for circITGA7 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |