Basic Information
| LncRNA/CircRNA Name | circVAPA |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | liver cancer |
| ICD-0-3 | C22.0 |
| Methods | qPCR, CCK-8, colony formation, and EdU assays |
| Sample | liver cancer cell lines |
| Expression Pattern | up-regulated |
| Function Description | circVAPA was upregulated in HCC cell lines and circVAPA depletion was associated with decreased HCC cell proliferation. circVAPA promotes PSAP expression through sequestering miR-377-3p. |
| Pubmed ID | 31368365 |
| Year | 2019 |
| Title | Circular RNA circVAPA Promotes Cell Proliferation in Hepatocellular Carcinoma |
External Links
| Links for circVAPA | GenBank HGNC NONCODE |
| Links for liver cancer | OMIM COSMIC |