Basic Information
| LncRNA/CircRNA Name | circ_102597 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | NA | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non functioning pituitary adenomas |
| ICD-0-3 | NA |
| Methods | qRT-PCR , immunohistochemistry , sanger sequencing |
| Sample | NFPAs invasive and the non-invasive tumor tissues? |
| Expression Pattern | down-regulated |
| Function Description | The expression of hsa_circRNA_102597, a downregulated circRNA, was significantly correlated with tumor diameter and Knosp grade. Hsa_circRNA_102597 alone or in combined with Ki-67 index was able to accurately differentiate invasive from non-invasive NFPAs as well as predict tumor progression/recurrence. |
| Pubmed ID | 31261542 |
| Year | 2019 |
| Title | Differential circular RNA expression profiles of invasive and non-invasive non-functioning pituitary adenomas |
External Links
| Links for circ_102597 | GenBank HGNC NONCODE |
| Links for non functioning pituitary adenomas | OMIM COSMIC |