Basic Information
| LncRNA/CircRNA Name | circ_100338 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | NA | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular cancer |
| ICD-0-3 | NA |
| Methods | qRT-PCR , western blot , MTT cell proliferation assay , Immunohistochemistry |
| Sample | HCC tissues and adjacent normal tissues,HCC cell line(MHCC97 ,SMMC7721 and Hep3B ,BEL7402) |
| Expression Pattern | up-regulated |
| Function Description | In conclusion, elevated circRNA-100338 activates mTOR signaling pathway in HCC via circRNA-100338/miR-141-3p/RHEB axis and associates with poor prognosis of hepatitis B-related HCC patients. |
| Pubmed ID | 31157168 |
| Year | 2019 |
| Title | CircRNA-100338 Is Associated With mTOR Signaling Pathway and Poor Prognosis in Hepatocellular Carcinoma |
External Links
| Links for circ_100338 | GenBank HGNC NONCODE |
| Links for hepatocellular cancer | OMIM COSMIC |