Basic Information
| LncRNA/CircRNA Name | circAKT3 |
| Synonyms | circ_0000199 |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | Cisplatin | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, luciferase reporter assay, RNA-seq, western blot |
| Sample | GC tissues and cell line |
| Expression Pattern | up-regulated |
| Function Description | The expression of circAKT3 was higher in CDDP-resistant GC tissues and cells than in CDDP-sensitive samples. |
| Pubmed ID | 30927924 |
| Year | 2019 |
| Title | Circular RNA AKT3 upregulates PIK3R1 to enhance cisplatin resistance in gastric cancer via miR-198 suppression. |
External Links
| Links for circAKT3 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |