Basic Information
| LncRNA/CircRNA Name | circPPP1R12A |
| Synonyms | circ_0000423 |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colon cancer |
| ICD-0-3 | C18 |
| Methods | qPCR, western blot, RNA-seq |
| Sample | CC tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | We firstly screened the expression profiles of human circRNAs in CC tissues and found that the expression of hsa_circ_0000423 (termed as circPPP1R12A) was significantly increased in CC tissues. |
| Pubmed ID | 30925892 |
| Year | 2019 |
| Title | A novel protein encoded by a circular RNA circPPP1R12A promotes tumor pathogenesis and metastasis of colon cancer via Hippo-YAP signaling. |
External Links
| Links for circPPP1R12A | GenBank HGNC NONCODE |
| Links for colon cancer | OMIM COSMIC |