Basic Information
| LncRNA/CircRNA Name | circLPAR1 |
| Synonyms | circ_0087960 |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | bladder cancer |
| ICD-0-3 | C67 |
| Methods | qPCR |
| Sample | muscle-invasive bladder cancer (MIBC) tissues,cell lines(T24,5637) |
| Expression Pattern | down-regulated |
| Function Description | The present study identified a novel circRNA, circ lysophosphatidic acid receptor 1 (LPAR1) (hsa_circ_0087960), derived from two exons 226 base pairs in length, in muscle-invasive bladder cancer (MIBC) tissues. circLPAR1 was identified to be lowly expressed in MIBC tissues in a cohort of 125 cases, and predicted a poor disease-specific survival time, compared with patients with high circLPAR1 expression |
| Pubmed ID | 30867795 |
| Year | 2019 |
| Title | circLPAR1 is a novel biomarker of prognosis for muscle-invasive bladder cancer with invasion and metastasis by miR-762. |
External Links
| Links for circLPAR1 | GenBank HGNC NONCODE |
| Links for bladder cancer | OMIM COSMIC |