Basic Information
| LncRNA/CircRNA Name | circ_0003998 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung adenocarcinoma |
| ICD-0-3 | C34 |
| Methods | luciferase reporter assay |
| Sample | LAD tissues,cell lines (A549/DTX ,H1299/DTX) |
| Expression Pattern | differential expressed |
| Function Description | Moreover, by using bioinformatics and luciferase reporter assays, we found that miR-326 was a direct target of hsa_circ_0003998. Functional analysis revealed that miR-326 mediated the effect of hsa_circ_0003998 on chemosensitivity. |
| Pubmed ID | 30764896 |
| Year | 2019 |
| Title | Hsa_circ_0003998 Promotes Chemoresistance via Modulation of miR-326 in Lung Adenocarcinoma Cells. |
External Links
| Links for circ_0003998 | GenBank HGNC NONCODE |
| Links for lung adenocarcinoma | OMIM COSMIC |