Basic Information
LncRNA/CircRNA Name | circPRKCI |
Synonyms | |
Region | |
Ensemble | |
Refseq |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | apoptosis | Drug | ||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | esophageal squamous cell carcinoma |
ICD-0-3 | NA |
Methods | qPCR, luciferase reporter assay, RIP |
Sample | ESCC tissues,cell line |
Expression Pattern | up-regulated |
Function Description | We found circ-PRKCI is obviously upregulated in esophageal squamous cell carcinoma and upregulation of circ-PRKCI stimulated cell migration and proliferation of ESCC cells. |
Pubmed ID | 30659640 |
Year | 2019 |
Title | Circular RNA circ-PRKCI functions as a competitive endogenous RNA to regulate AKT3 expression by sponging miR-3680-3p in esophageal squamous cell carcinoma. |
External Links
Links for circPRKCI | GenBank HGNC NONCODE |
Links for esophageal squamous cell carcinoma | OMIM COSMIC |