Basic Information
| LncRNA/CircRNA Name | circZNF609 |
| Synonyms | circ_0000615 |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | renal cancer |
| ICD-0-3 | C64.9 |
| Methods | qRT??CR, RNase R digestion, Western blot, Dual??uciferase reporter assay, Matrigel assay, Cell proliferation, RIP |
| Sample | renal carcinoma cells A??98, ACHN, OS??C??, 769??, G??01, and the normal renal epithelial cell line KiMA |
| Expression Pattern | up-regulated |
| Function Description | circ-ZNF609 is significantly increased in renal carcinoma cell lines. In addition, the high expression of circ-ZNF609 promotes cell proliferation and invasion ability |
| Pubmed ID | 30478938 |
| Year | 2018 |
| Title | CircRNA ZNF609 functions as a competitive endogenousRNA to regulate FOXP4 expression by sponging miR??38??p in renal carcinoma |
External Links
| Links for circZNF609 | GenBank HGNC NONCODE |
| Links for renal cancer | OMIM COSMIC |