Basic Information
| LncRNA/CircRNA Name | circ_100876 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | esophageal squamous cell carcinoma |
| ICD-0-3 | NA |
| Methods | RT-qPCR, CCK-8, colony-formation, and 5-ethynyl-2??deoxyuridine (EdU)-incorporation assays, Animal study, Flow cytometric analyses, Transwell migration and invasion assays, Western blotting assa |
| Sample | ESCC tissues, ESCC cell lines Eca-109, TE-1, KYSE-410, KYSE-150, HEEC |
| Expression Pattern | up-regulated |
| Function Description | CircRNA_100876 expression was upregulated (P,0.05) and was negatively correlated with survival outcome (P,0.05) in ESCC.?Inhibition of proliferation, migration, invasion, and epithelial mesenchymal transition progression was confirmed after circRNA_100876 depletion. |
| Pubmed ID | 30425526 |
| Year | 2018 |
| Title | Contribution of dysregulated circRNA_100876 to proliferation and metastasis of esophageal squamous cell carcinoma |
External Links
| Links for circ_100876 | GenBank HGNC NONCODE |
| Links for esophageal squamous cell carcinoma | OMIM COSMIC |