Detail
| LncRNA Name | ENST00000521815 |
| Synonyms | CASC19, CARLo-6, LINC01245 |
| Region | GRCh38_8:127072694-127227541 Sequence |
| Ensembl | ENSG00000254166 |
| RefSeq | NR_120364 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR |
| Sample | colorectal cancer tissues, cell lines (LOVO, CACO2, DLD1, HCT8, RKO, FHC) |
| Expression Pattern | up-regulated |
| Function Description | The expression of CASC19 in colorectal cancer was significantly higher than those in adjacent normal mucosa tissues (t=5.527, P<0.000 1) and was associated with metastasis (P=0.044). Knockdown of CASC19 expression in CRC inhibited the migration ability of CRC in vitro.CASC19 expression is not associated with age, gender, or tumor site/differentiation but with tumor size, lymph node metastasis, and distant metastasis, suggesting high CASC19 expression may promote CRC metastasis. |
| Pubmed ID | 29338818 |
| Year | 2017 |
| Title | Expression and Function of Long Non-coding RNA CASC19 in Colorectal Cancer. |
| External Links |
| Links for ENST00000521815 | GenBank HGNC lncrnadb Noncode |
| Links for colorectal cancer | Omim Cosmic |
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