Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name AFAP1-AS1
   Synonyms AFAP1-AS1, AFAP1-AS, AFAP1AS, LOC84740, MGC10981
   Region GRCh38_4:7754090-7778928    Sequence
   Ensembl ENSG00000272620
   RefSeq NR_026892
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name gastric cancer
   ICD-0-3 C16  
   Methods qPCR, Western blot, etc.
   Sample gastric cancer tissues, cell lines (AGS, BGC-823, MGC-803, SGC-7901)
   Expression Pattern up-regulated
   Function Description

We found that lncRNA AFAP1-AS1 was upregulated in GC and play as an important biomarker of prognosis in GC patients. Therefore, lncRNA AFAP1-AS1 may be a biomarker for prognosis and a therapeutic target of GC.

   Pubmed ID 28975981
   Year 2017
   Title Increased lncRNA AFAP1-AS1 expression predicts poor prognosis and promotes malignant phenotypes in gastric cancer
   External Links
   Links for  AFAP1-AS1 GenBank       HGNC       lncrnadb       Noncode
   Links for  gastric cancer Omim       Cosmic

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