Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

LncRNA centric

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   LncRNA Name AB019562
   Synonyms NA
   Region NA    Sequence
   Ensembl NA
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name hepatocellular carcinoma
   ICD-0-3 C22.0  M8170/3
   Methods qPCR etc.
   Sample HCC tissues, cell lines (SMMC-7721, PLC/PRF/5, C3AHCC, THLE-3)
   Expression Pattern up-regulated
   Function Description

AB019652 is upregulated in HCC tissues and cultured HCC cells. AB019562 knockdown increased the apoptotic rates of the two cell lines and activated the expression of caspase3, but not caspase8.For patients in the late stage, the introduction of sorafenib can improve survival rates, but remains limited.

   Pubmed ID 28534955
   Year 2017
   Title Long non-coding RNA AB019562 promotes cell proliferation and metastasis in human hepatocellular carcinoma.
   External Links
   Links for  AB019562 GenBank       HGNC       lncrnadb       Noncode
   Links for  hepatocellular carcinoma Omim       Cosmic

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