Detail
| LncRNA Name | FENDRR |
| Synonyms | FENDRR, FOXF1-AS1, TCONS_00024240, lincFOXF1, onco-lncRNA-21 |
| Region | GRCh38_16:86474529-86509099 Sequence |
| Ensembl | ENSG00000268388 |
| RefSeq | NR_033925 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR, in vitro knockdown etc. |
| Sample | cell lines (MCF-7, BT-474, SK-BR-3, HCC1937, MDA-MB-231), breast cancer tissues |
| Expression Pattern | down-regulated |
| Function Description | FENDRR inhibits breast cancer cell proliferation and migration and promotes cell apoptosis, while FENDRR knockdown promotes breast cancer cell proliferation and migration and suppresses cell apoptosis. FENDRR overexpression could inhibit tumor growth in a xenograft model. FENDRR inhibits breast cancer cell proliferation, promotes cell apoptosis, and is associated with good prognosis in breast cancer. |
| Pubmed ID | 29559798 |
| Year | 2018 |
| Title | Long non-coding RNA FENDRR inhibits cell proliferation and is associated with good prognosis in breast cancer. |
| External Links |
| Links for FENDRR | GenBank HGNC lncrnadb Noncode |
| Links for breast cancer | Omim Cosmic |
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