Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name FER1L4
   Synonyms FER1L4, C20orf124
   Region GRCh38_20:35558737-35607562    Sequence
   Ensembl ENSG00000088340
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name glioblastoma
   ICD-0-3  M9440/3
   Methods qPCR etc.
   Sample glioma tissues, cell lines (U373-MG, U251, LN-18, U87-MG and SHG-44)
   Expression Pattern down-regulated
   Function Description

FER1L4 was downregulated in 91.80% of gastric cancer tissues studied.low expression of FER1L4 was associated with tumor size, histological staging, tumor infiltration depth, lymph node metastasis, distant metastasis, tumor-node-metastasis staging, angioneurotic infiltration and serum CA72-4 antigen levels.Patients that receive surgical treatment for this disease typically have a poor prognosis, particularly those with glioblastoma multiforme (GBM), for which the average survival time is <2 years.etal bovine serum (FBS), 0.25% trypsin and Dulbecco's modified Eagle's medium (DMEM) were purchased from Invitrogen.

   Pubmed ID 28789454
   Year 2017
   Title Long non-coding RNA Fer-1-like family member 4 is overexpressed in human glioblastoma and regulates the tumorigenicity of glioma cells.
   External Links
   Links for  FER1L4 GenBank       HGNC       lncrnadb       Noncode
   Links for  glioblastoma Omim       Cosmic

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