Detail
| LncRNA Name | FEZF1-AS1 |
| Synonyms | NR_036484 |
| Region | GRCh38_7:122303658-122310077 Sequence |
| Ensembl | ENSG00000230316 |
| RefSeq | NR_036484 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 M8170/3 |
| Methods | qPCR, Western blot, etc. |
| Sample | The human HCC cells( HepG2, SK-hep1, Huh7, HCCLM3), normal liver cell line (LO2) |
| Expression Pattern | up-regulated |
| Function Description | In conclusion, the present study for the first time demonstrated that FEZF1-AS1 serves as an oncogenic lncRNA in human HCC and implicated FEZF1-AS1 as a valuable therapeutic target for HCC treatment. Kaplan-Meier analysis of overall survival (OS) in 139 HCC patients based on FEZF1-AS1 expression. |
| Pubmed ID | 29957463 |
| Year | 2018 |
| Title | Long non-coding RNA FEZF1-AS1 promotes cell invasion and epithelial-mesenchymal transition through JAK2/STAT3 signaling pathway in human hepatocellular carcinoma. |
| External Links |
| Links for FEZF1-AS1 | GenBank HGNC lncrnadb Noncode |
| Links for hepatocellular carcinoma | Omim Cosmic |
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