Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name FGF14-AS2
   Synonyms FGF14-AS2
   Region GRCh38_13:102394630-102395703    Sequence
   Ensembl ENSG00000272143
   RefSeq NR_036487
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name breast cancer
   ICD-0-3 C50  
   Methods qPCR, RIP etc.
   Sample breast cancer tissues
   Expression Pattern down-regulated
   Function Description

In this study, we demonstrated that FGF14 antisense RNA 2 (FGF14-AS2), a novel long non-coding RNA, was significantly down-regulated in breast cancer tissue compared with adjacent normal tissue both in validated cohort and TCGA cohort. Reduced expression of FGF14-AS2 was correlated with larger tumor size, more lymph node metastasis and advanced clinical stage in both cohorts.

   Pubmed ID 26820525
   Year 2016
   Title A novel long non-coding RNA FGF14-AS2 is correlated with progression and prognosis in breast cancer.
   External Links
   Links for  FGF14-AS2 GenBank       HGNC       lncrnadb       Noncode
   Links for  breast cancer Omim       Cosmic

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