Detail
| LncRNA Name | AFAP1-AS1 |
| Synonyms | AFAP1-AS1, AFAP1-AS, AFAP1AS, LOC84740, MGC10981 |
| Region | GRCh38_4:7754090-7778928 Sequence |
| Ensembl | ENSG00000272620 |
| RefSeq | NR_026892 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 M8046/3 |
| Methods | qPCR, Western blot, RIP etc. |
| Sample | non small cell lung cancer tissues, Cell lines (16HBE, A549, SPC-A1 and H1299) |
| Expression Pattern | up-regulated |
| Function Description | AFAP1-AS1 expression was increased in NSCLC tissues and was correlated with clinical outcomes of NSCLC. Over-expression of AFAP1-AS1 level reveals a poor overall survival time (OS) of patients with NSCLC and could be regarded AS an independent predictor for OS |
| Pubmed ID | 29793547 |
| Year | 2018 |
| Title | Long noncoding RNA AFAP1-AS1 predicts a poor prognosis and regulates non-small cell lung cancer cell proliferation by epigenetically repressing p21 expression |
| External Links |
| Links for AFAP1-AS1 | GenBank HGNC lncrnadb Noncode |
| Links for non small cell lung cancer | Omim Cosmic |
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