Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name FOXD2-AS1
   Synonyms NA
   Region GRCh38_1:47432133-47434641    Sequence
   Ensembl ENSG00000237424
   RefSeq NR_026878
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name nasopharyngeal cancer
   ICD-0-3 C11  
   Methods qPCR, Western blot, in vitro knockdown etc.
   Sample cell lines (SUNE-1, CNE-1, HNE-1, CNE-2, C666-1,HONE-1), NPC tissues
   Expression Pattern up-regulated
   Function Description

The aberrant overexpression of FOXD2-AS1 indicated the poor prognosis of NPC patients. Silence of FOXD2-AS1 was able to repress NPC cell growth in vitro while overexpression of FOXD2-AS1 inversed this process.

   Pubmed ID 29248577
   Year 2017
   Title Long non-coding RNA FOXD2-AS1 aggravates nasopharyngeal carcinoma carcinogenesis by modulating miR-363-5p/S100A1 pathway
   External Links
   Links for  FOXD2-AS1 GenBank       HGNC       lncrnadb       Noncode
   Links for  nasopharyngeal cancer Omim       Cosmic

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