Detail
| LncRNA Name | FOXD2-AS1 |
| Synonyms | NA |
| Region | GRCh38_1:47432133-47434641 Sequence |
| Ensembl | ENSG00000237424 |
| RefSeq | NR_026878 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 M8046/3 |
| Methods | qPCR, RNAi, Western blot, Luciferase reporter assay, MTT assay etc. |
| Sample | NSCLC tissues, cell lines (H1299, A549, H1650 and H2291) |
| Expression Pattern | up-regulated |
| Function Description | We found that lncRNA FOXD2-AS1 is significantly up-regulated in NSCLC tissues. Loss- and gain-function assays revealed that FOXD2-AS1 promotes NSCLC cell growth and NSCLC tumor progression. Furthermore, we also revealed that FOXD2-AS1 modulates Wnt/B-catenin signaling in NSCLC cells. |
| Pubmed ID | 28132805 |
| Year | 2017 |
| Title | Highly expressed long non-coding RNA FOXD2-AS1 promotes non-small cell lung cancer progression via Wnt/B-catenin signaling. |
| External Links |
| Links for FOXD2-AS1 | GenBank HGNC lncrnadb Noncode |
| Links for non small cell lung cancer | Omim Cosmic |
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