Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name AFAP1-AS1
   Synonyms AFAP1-AS1, AFAP1-AS, AFAP1AS, LOC84740, MGC10981
   Region GRCh38_4:7754090-7778928    Sequence
   Ensembl ENSG00000272620
   RefSeq NR_026892
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name gastric cancer
   ICD-0-3 C16  
   Methods qPCR, Western blot etc.
   Sample gastric cancer tissues, cell lines (GES-1, AGS, BGC-823, MKN-45 and SGC-7901)
   Expression Pattern up-regulated
   Function Description

The expression of AFAP1-AS1 was significantly increased in the primary tumor tissues of GC patients with lymph node metastasis or tumor node metastasis stage. The overexpression of AFAP1-AS1 was positively associated with the poor survival rates of GC patients.

   Pubmed ID 29805596
   Year 2018
   Title Long non-coding RNA AFAP1-antisense RNA 1 promotes the proliferation, migration and invasion of gastric cancer cells and is associated with poor patient survival
   External Links
   Links for  AFAP1-AS1 GenBank       HGNC       lncrnadb       Noncode
   Links for  gastric cancer Omim       Cosmic

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