Detail
| LncRNA Name | FTH1P3 |
| Synonyms | FTH1P3, FTHL3, FTHL3P |
| Region | GRCh38_2:27392784-27393367 Sequence |
| Ensembl | ENSG00000213453 |
| RefSeq | NA |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | uveal melanoma |
| ICD-0-3 | C69.9 M8720/3 |
| Methods | qPCR, Western blot etc. |
| Sample | cell lines (OCM-1A, MUM-2C, C918, MUM-2B) |
| Expression Pattern | up-regulated |
| Function Description | lncRNA FTH1P3 was commonly up-regulated in uveal melanoma cell lines and tissues and acted as an oncogene in uveal melanoma progression by inhibiting miR-224-5p expression. These results suggest that lncRNA FTH1P3 plays a crucial role in uveal melanoma and investigation of the underlying mechanism may be a target for the treatment of uveal melanoma. |
| Pubmed ID | 29095823 |
| Year | 2017 |
| Title | Long non-coding RNA FTH1P3 facilitates uveal melanoma cell growth and invasion through miR-224-5p |
| External Links |
| Links for FTH1P3 | GenBank HGNC lncrnadb Noncode |
| Links for uveal melanoma | Omim Cosmic |
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