Detail
| LncRNA Name | FTX |
| Synonyms | FTX, LINC00182, MIR374AHG, NCRNA00182, FLJ33139 |
| Region | GRCh38_X:73946555-74293574 Sequence |
| Ensembl | ENSG00000230590 |
| RefSeq | NR_028379 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✔ |
| Cancer Name | uveal melanoma |
| ICD-0-3 | C69.9 M8720/3 |
| Methods | qPCR, RNAi, RNA-FISH, Cell migration and invasion assay etc. |
| Sample | cell lines (HDF, MUM2B, OCM1, OCM1A, OM431, SP6.5, and 293T) |
| Expression Pattern | down-regulated |
| Function Description | Real-time PCR results showed that JPX expression was extremely weak in UM cells, whereas JPX expression was significantly increased in CANT1-expressing cells. Similarly, after CANT1 overexpression, FTX expression was markedly enhanced compared with that in control UM cells. |
| Pubmed ID | 28330694 |
| Year | 2017 |
| Title | CANT1 lncRNA Triggers Efficient Therapeutic Efficacy by Correcting Aberrant lncing Cascade in Malignant Uveal Melanoma. |
| External Links |
| Links for FTX | GenBank HGNC lncrnadb Noncode |
| Links for uveal melanoma | Omim Cosmic |
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