Detail
| LncRNA Name | FTX |
| Synonyms | FTX, LINC00182, MIR374AHG, NCRNA00182, FLJ33139 |
| Region | GRCh38_X:73946555-74293574 Sequence |
| Ensembl | ENSG00000230590 |
| RefSeq | NR_028379 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | glioma |
| ICD-0-3 | M9380/3 |
| Methods | qPCR, Cell transfection, Western blot, MTT assay etc. |
| Sample | glioma tissues, cell lines (U87MG and LN18) |
| Expression Pattern | up-regulated |
| Function Description | the expression of FTX and miR-342-3p was associated with progression of gliomas. FTX directly inhibited the expression of miR-342-3p, which subsequently regulates the expression of AEG-1. Collectively, FTX is critical for proliferation and invasion of glioma cells by regulating miR-342-3p and AEG-1. |
| Pubmed ID | 28112756 |
| Year | 2017 |
| Title | Long noncoding RNA FTX is upregulated in gliomas and promotes proliferation and invasion of glioma cells by negatively regulating miR-342-3p. |
| External Links |
| Links for FTX | GenBank HGNC lncrnadb Noncode |
| Links for glioma | Omim Cosmic |
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