Detail
| LncRNA Name | AFAP1-AS1 |
| Synonyms | AFAP1-AS1, AFAP1-AS, AFAP1AS, LOC84740, MGC10981 |
| Region | GRCh38_4:7754090-7778928 Sequence |
| Ensembl | ENSG00000272620 |
| RefSeq | NR_026892 |
| Circulating | ✘ |
| Drug-resisitant | ✔ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | laryngeal squamous cell cancer |
| ICD-0-3 | C32.3 |
| Methods | qPCR,Luciferase reporter assay,Western blot,etc. |
| Sample | laryngeal specimens and normal tissues |
| Expression Pattern | up-regulated |
| Function Description | Taken together,these results suggest that, AFAP1-AS1 can serve as a prognostic biomarker in laryngeal carcinoma and that, miR-320a has the potential to improve standard therapeutic approaches to the disease, especially for cases in which cancer cell stemness and drug resistance. |
| Pubmed ID | 29971915 |
| Year | 2018 |
| Title | Long non-coding RNA AFAP1-AS1/miR-320a/RBPJ axis regulates laryngeal carcinoma cell stemness and chemoresistance. |
| External Links |
| Links for AFAP1-AS1 | GenBank HGNC lncrnadb Noncode |
| Links for laryngeal squamous cell cancer | Omim Cosmic |
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