Detail
LncRNA Name | GACAT3 |
Synonyms | GACAT3, LINC01458, lncRNA-AC130712 |
Region | GRCh38_2:16050427-16085801 Sequence |
Ensembl | ENSG00000236289 |
RefSeq | NR_126559 |
Circulating | ✘ |
Drug-resisitant | ✔ |
Prognostic | ✘ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | non small cell lung cancer |
ICD-0-3 | C34 M8046/3 |
Methods | qPCR, Western blot, Luciferase reporting assay etc. |
Sample | cell lines (A549, H157,HCC827, H838), NSCLC tissue |
Expression Pattern | up-regulated |
Function Description | Overexpression of ectopic GACAT3 in A549 cells promoted cell proliferation and migration, and enhanced the sensitivity of lung cancer cells to radiotherapy. |
Pubmed ID | 29565489 |
Year | 2018 |
Title | High expression of lncRNA GACAT3 inhibits invasion and metastasis of non-small cell lung cancer to enhance the effect of radiotherapy. |
External Links |
Links for GACAT3 | GenBank HGNC lncrnadb Noncode |
Links for non small cell lung cancer | Omim Cosmic |
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