Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name GACAT3
   Synonyms GACAT3, LINC01458, lncRNA-AC130712
   Region GRCh38_2:16050427-16085801    Sequence
   Ensembl ENSG00000236289
   RefSeq NR_126559
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name non small cell lung cancer
   ICD-0-3 C34  M8046/3
   Methods qPCR, Western blot, Luciferase reporting assay etc.
   Sample cell lines (A549, H157,HCC827, H838), NSCLC tissue
   Expression Pattern up-regulated
   Function Description

Overexpression of ectopic GACAT3 in A549 cells promoted cell proliferation and migration, and enhanced the sensitivity of lung cancer cells to radiotherapy.

   Pubmed ID 29565489
   Year 2018
   Title High expression of lncRNA GACAT3 inhibits invasion and metastasis of non-small cell lung cancer to enhance the effect of radiotherapy.
   External Links
   Links for  GACAT3 GenBank       HGNC       lncrnadb       Noncode
   Links for  non small cell lung cancer Omim       Cosmic

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