Detail
LncRNA Name | GACAT3 |
Synonyms | GACAT3, LINC01458, lncRNA-AC130710 |
Region | GRCh38_2:16050427-16085801 Sequence |
Ensembl | ENSG00000236289 |
RefSeq | NR_126559 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✔ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | breast cancer |
ICD-0-3 | C50 |
Methods | qPCR, Luciferase activity assay, etc. |
Sample | breast cancer tissues, cell lines (MCF-7, MDA-MB-231, MDA-MB-468, MDA-MB-453, T-47D, SK-BR-3, MCF-10A) |
Expression Pattern | up-regulated |
Function Description | GACAT3 promotes breast cancer malignancy by sponging miR-497, leading to the enhancement of its endogenous target CCND2. |
Pubmed ID | 29945347 |
Year | 2018 |
Title | LncRNA GACAT3 predicts poor prognosis and promotes cell proliferation in breast cancer through regulation of miR-497/CCND2. |
External Links |
Links for GACAT3 | GenBank HGNC lncrnadb Noncode |
Links for breast cancer | Omim Cosmic |
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