Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name GACAT3
   Synonyms GACAT3, LINC01458, lncRNA-AC130710
   Region GRCh38_2:16050427-16085801    Sequence
   Ensembl ENSG00000236289
   RefSeq NR_126559
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name breast cancer
   ICD-0-3 C50  
   Methods qPCR, Luciferase activity assay, etc.
   Sample breast cancer tissues, cell lines (MCF-7, MDA-MB-231, MDA-MB-468, MDA-MB-453, T-47D, SK-BR-3, MCF-10A)
   Expression Pattern up-regulated
   Function Description

GACAT3 promotes breast cancer malignancy by sponging miR-497, leading to the enhancement of its endogenous target CCND2.

   Pubmed ID 29945347
   Year 2018
   Title LncRNA GACAT3 predicts poor prognosis and promotes cell proliferation in breast cancer through regulation of miR-497/CCND2.
   External Links
   Links for  GACAT3 GenBank       HGNC       lncrnadb       Noncode
   Links for  breast cancer Omim       Cosmic

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