Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name AFAP1-AS1
   Synonyms AFAP1-AS1, AFAP1-AS, AFAP1AS, LOC84740, MGC10981
   Region GRCh38_4:7754090-7778928    Sequence
   Ensembl ENSG00000272620
   RefSeq NR_026892
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name non small cell lung cancer
   ICD-0-3 C34  M8046/3
   Methods qPCR, etc.
   Sample lung cancer tissues, normal tissues.
   Expression Pattern up-regulated
   Function Description

In conclusion, it was demonstrated that lncRNA AFAP1?AS1 is overexpressed in NSCLC and an unfavorable biomarker for patients with NSCLC. Upregulation of HOTAIR in lung tumor tissues is associated with metastasis, drug resistance and poor survival time in patients with lung cancer.

   Pubmed ID 29963138
   Year 2018
   Title Long noncoding RNA AFAP1-AS1 is upregulated in NSCLC and associated with lymph node metastasis and poor prognosis.
   External Links
   Links for  AFAP1-AS1 GenBank       HGNC       lncrnadb       Noncode
   Links for  non small cell lung cancer Omim       Cosmic

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