Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

LncRNA centric

Cancer centric

Advanced search

Drug resistant

Circulating

Prognosis

Detail


   LncRNA Name GADD45G
   Synonyms GADD45G, CR6, DDIT2, GADD45gamma, GRP17
   Region GRCh38_9:89605013-89606555    Sequence
   Ensembl ENSG00000130222
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name pituitary adenoma
   ICD-0-3 C75.1  M8272/0
   Methods qPCR etc.
   Sample pituitary tumor tissues
   Expression Pattern down-regulated
   Function Description

In summary, MEG3 and GADD45γexpression was significantly lost in most clinically non-functioning adenomas (78 and 92%, respetcively). Other assessed pituitary tumor phenotypes expressed both genes at significantly different levels, and, in some cases, with overexpression.

   Pubmed ID 21850407
   Year 2012
   Title Expression of cell growth negative regulators MEG3 and GADD45γ is lost in most sporadic human pituitary adenomas.
   External Links
   Links for  GADD45G GenBank       HGNC       lncrnadb       Noncode
   Links for  pituitary adenoma Omim       Cosmic

CopyRight © College of Bioinformatics Science and Technology, Harbin Medical University, China.