Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name GAPLINC
   Synonyms GAPLINC, LINC01540, TCONS_00026238, lncRNA-uc002kmd.1
   Region GRCh38_18:3466250-3478978    Sequence
   Ensembl ENSG00000266835
   RefSeq NR_110429
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name gastric cancer
   ICD-0-3 C16  
   Methods qPCR, Western blot etc.
   Sample gastric cancer tissues, cell lines (KATO III, HGC-27, and SNU-1)
   Expression Pattern up-regulated
   Function Description

The lncRNA GAPLINC expression was upregulated and positively correlated with MAPK1 expression in gastric cancer tissues and cells. lncRNA GAPLINC promotes gastric cancer cell proliferation by acting as a molecular sponge of miR-378 to modulate MAPK1 expression.

   Pubmed ID 29785127
   Year 2018
   Title Long noncoding RNA GAPLINC promotes gastric cancer cell proliferation by acting as a molecular sponge of miR-378 to modulate MAPK1 expression
   External Links
   Links for  GAPLINC GenBank       HGNC       lncrnadb       Noncode
   Links for  gastric cancer Omim       Cosmic

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