Detail
| LncRNA Name | AGAP2-AS1 |
| Synonyms | AGAP2-AS1, PUNISHER, LOC100130776, PUNISHER |
| Region | GRCh38_12:57726271-57728356 Sequence |
| Ensembl | ENSG00000255737 |
| RefSeq | NR_027032 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | glioma |
| ICD-0-3 | M9380/3 |
| Methods | microarray, qPCR, RNAi, Flow cytometry assay, Cell proliferation assay etc. |
| Sample | glioma tissues, cell lines (LN229 and U87MG) |
| Expression Pattern | up-regulated |
| Function Description | The expression of four lncRNAs in different grades showed that AGAP2-AS1, LINC01198 and MIR155HG were increased with tumor grade, while TPT1-AS1 was decreased. Knockdown of AGAP2-AS1 can inhibit the cell proliferation, migration and invasion, while increase the apoptosis cell rates in vitro. |
| Pubmed ID | 27764782 |
| Year | 2016 |
| Title | LncRNA profile study reveals four-lncRNA signature associated with the prognosis of patients with anaplastic gliomas. |
| External Links |
| Links for AGAP2-AS1 | GenBank HGNC lncrnadb Noncode |
| Links for glioma | Omim Cosmic |
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