Detail
| LncRNA Name | GAS5 |
| Synonyms | GAS5, NCRNA00030, SNHG2, ENST00000456293.5, GAS5-007 |
| Region | GRCh38_1:173863900-173868882 Sequence |
| Ensembl | ENSG00000234741 |
| RefSeq | NR_002578 |
| Circulating | ✔ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✔ |
| TF | ✘ |
| Methylation | ✔ |
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR etc. |
| Sample | GC tissues |
| Expression Pattern | differential expression |
| Function Description | Genotype del/del was significantly associated with a higher survival rate. Patients with late tumor stage were found to have a significantly lower rate of genotype del/del than those with an early tumor stage . Patients with UICC III and IV were found to have a significantly lower rate of genotype del/del than those with UICC I and II. The variant rs145204276 of GAS5 is associated with the development and prognosis of GC.The allele del of rs145204276 is associated with a remarkably lower incidence of cancer progression and metastasis. Methylation percentage of the 7th CpG site significantly correlated with GAS5 expression in the tumor tissues |
| Pubmed ID | 29557411 |
| Year | 2018 |
| Title | The Variant rs145204276 of GAS5 is Associated with the Development and Prognosis of Gastric Cancer. |
| External Links |
| Links for GAS5 | GenBank HGNC lncrnadb Noncode |
| Links for gastric cancer | Omim Cosmic |
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