Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

LncRNA centric

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   LncRNA Name GAS5
   Synonyms GAS5, NCRNA00030, SNHG2, ENST00000456293.5, GAS5-007
   Region GRCh38_1:173863900-173868882    Sequence
   Ensembl ENSG00000234741
   RefSeq NR_002578
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name breast cancer
   ICD-0-3 C50  
   Methods qPCR etc.
   Sample breast cancer tissues, blood
   Expression Pattern down-regulated
   Function Description

Analysis in the 39 paired preoperative and postoperative plasma samples showed that lower GAS5 levels appeared in the patients with a high Ki67 proliferation index before surgery and the patients with a positive lymph node metastasis state after surgery. Plasma lncRNA GAS5 may have the potential to assess the surgical effects and prognosis for BC patients

   Pubmed ID 26662314
   Year 2015
   Title Circulating long noncoding RNA GAS5 as a potential biomarker in breast cancer for assessing the surgical effects
   External Links
   Links for  GAS5 GenBank       HGNC       lncrnadb       Noncode
   Links for  breast cancer Omim       Cosmic

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