Detail
| LncRNA Name | GAS5 |
| Synonyms | GAS5, NCRNA00030, SNHG2, ENST00000456293.5, GAS5-007 |
| Region | GRCh38_1:173863900-173868882 Sequence |
| Ensembl | ENSG00000234741 |
| RefSeq | NR_002578 |
| Circulating | ✘ |
| Drug-resisitant | ✔ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | prostate cancer |
| ICD-0-3 | C61.9 |
| Methods | qPCR, RNAi etc. |
| Sample | cell lines (22Rv1, PC-3 etc.) |
| Expression Pattern | up-regulated |
| Function Description | GAS5 promotes the apoptosis of prostate 34 cells, and exonic sequence, i.e. GAS5 lncRNA, is sufficient to mediate this activity. Abnormally low levels of 35 GAS5 expressionmay therefore reduce the effectiveness of chemotherapeutic agents. |
| Pubmed ID | 23676682 |
| Year | 2013 |
| Title | Long non-coding RNA GAS5 regulates apoptosis in prostate cancer cell lines. |
| External Links |
| Links for GAS5 | GenBank HGNC lncrnadb Noncode |
| Links for prostate cancer | Omim Cosmic |
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