Detail
| LncRNA Name | GAS5 |
| Synonyms | GAS5, NCRNA00030, SNHG2, ENST00000456293.5, GAS5-007 |
| Region | GRCh38_1:173863900-173868882 Sequence |
| Ensembl | ENSG00000234741 |
| RefSeq | NR_002578 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR etc. |
| Sample | cell lines (HEK 293T, LNCaP, W7.2c etc.) |
| Expression Pattern | down-regulated |
| Function Description | We have found that, in some cell lines, GAS5 expression induces growth arrest and apoptosis independently of other stimuli. GAS5 transcript levels were significantly reduced in breast cancer samples relative to adjacent unaffected normal breast epithelial tissues. |
| Pubmed ID | 18836484 |
| Year | 2009 |
| Title | GAS5, a non-protein-coding RNA, controls apoptosis and is downregulated in breast cancer. |
| External Links |
| Links for GAS5 | GenBank HGNC lncrnadb Noncode |
| Links for breast cancer | Omim Cosmic |
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