Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name GAS5
   Synonyms GAS5, NCRNA00030, SNHG2, ENST00000456293.5, GAS5-007
   Region GRCh38_1:173863900-173868882    Sequence
   Ensembl ENSG00000234741
   RefSeq NR_002578
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name prostate cancer
   ICD-0-3 C61.9  
   Methods qPCR etc.
   Sample cell lines (HEK 293T, LNCaP, W7.2c etc.)
   Expression Pattern down-regulated
   Function Description

Real-time RTî??PCR was therefore carried out and the level of GAS5 expression was quantified in these cell lines relative to 22Rv1. 22Rv1, P4E6 and PNT2C2 cell linesexpressed similar levels of GAS5, whereas LNCaP and PC3 expressed much lower levels of GAS5.

   Pubmed ID 18836484
   Year 2009
   Title GAS5, a non-protein-coding RNA, controls apoptosis and is downregulated in breast cancer.
   External Links
   Links for  GAS5 GenBank       HGNC       lncrnadb       Noncode
   Links for  prostate cancer Omim       Cosmic

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